Daily Statin Medication Reduces Risk of Major Cardiovascular Events by More Than One-Third in People Living with HIV
By Noah Brown
The risk of cardiovascular diseases, including myocardial infarction and stroke, has been shown to be roughly twice as high in people living with HIV than the general population, creating an urgent need to test prevention strategies to ensure healthier, longer lives. In the first large-scale global clinical trial, Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE), to test a primary cardiovascular prevention strategy in individuals living with HIV, investigators from Massachusetts General Hospital (MGH), a founding member of Mass General Brigham (MGB), found that HIV positive participants who took a daily statin decreased their risk of major adverse cardiovascular events (MACE) by more than a third, and reduced rates of MACE or death by over 20%. The findings are published in the New England Journal of Medicine.