Marissa Diggs

February 28, 2024

Recommendations for Statins in People with HIV from the DHHS/ACC/AHA/HIVMA

The Department of Health and Human Services Guidelines Panel for the Use of Antiretroviral Agents in Adults and Adolescents with HIV (the Panel) has developed recommendations […]
February 21, 2024

Effects of Pitavastatin on Coronary Artery Disease and Inflammatory Biomarkers in HIV: Mechanistic Substudy of the REPRIEVE Randomized Clinical Trial

Abstract Importance  Cardiovascular disease (CVD) is increased in people with HIV (PWH) and is characterized by premature noncalcified coronary plaque. In the Randomized Trial to Prevent Vascular […]
January 22, 2024

REPRIEVE Will Forever Change Our Approach to Statin Use in People Living With HIV

By David Alain Wohl, MD While it’s not new, injected, implanted, or even prohibitively expensive, it is the medication studied in the most important HIV-related clinical […]
January 12, 2024

Risk Factors for Clonal Hematopoiesis of Indeterminate Potential in People with HIV: a report from the REPRIEVE Trial

Abstract Key Points Clonal hematopoiesis of Indeterminate Potential (CHIP), the clonal expansion of myeloid cells with leukemogenic mutations, results in increased coronary artery disease (CAD) risk. […]
January 8, 2024

CMV IgG is Associated with Physical Function but not Muscle Density in People with HIV

Abstract Background Cytomegalovirus (CMV) seropositivity is associated with poor outcomes, including physical function impairment, in people without HIV. We examined associations between CMV IgG titer and […]
January 5, 2024

NEJM Journal Watch Infectious Diseases Top Stories of 2023

By Rajesh T. Gandhi The editors present their choices of the most important articles from the year. Read the full article here.
December 15, 2023

British Experts Recommend Statins for All HIV-Positive People 40 and Older

By Liz Highleyman The British HIV Association (BHIVA) now recommends that all people living with HIV who are ages 40 and older should be offered a statin […]
December 12, 2023

BHIVA rapid guidance on the use of statins for primary prevention of cardiovascular disease in people living with HIV

November 21, 2023 In cohort studies, compared to the general population or controls without HIV, people living with HIV are at greater risk of atherosclerotic cardiovascular […]
November 30, 2023

World AIDS Day: Research from Across Mass General Brigham

November 29, 2023 December 1 marks the 35th commemoration of World AIDS Day, an annual event that reminds us that HIV and HIV-related stigma remain public […]