Marissa Diggs

July 14, 2023

Statin use in people living with HIV

By Priya Venkatesan The REPRIEVE trial has shown a benefit of statins in reducing the risk of cardiovascular events in people living with HIV, but many […]
July 10, 2023

Associations of Muscle Density and Area with Coronary Artery Plaque and Physical Function

Abstract Objective Skeletal muscle quality and mass are important for maintaining physical function during advancing age. We leveraged baseline data from REPRIEVE to evaluate whether paraspinal muscle density […]
May 3, 2023

Daily Statin Trial for People With HIV Halted Early for Clear Benefit

By Emily Harris People with HIV and a low to moderate traditional risk of cardiovascular disease who took a daily 4-mg dose of pitavastatin reduced their risk […]
April 13, 2023

Statin Reduces Cardiovascular Risk for People With HIV

By Liz Highleyman Large trial finds that pitavastatin lowered the risk for major cardiovascular events by 35%. Read the full article here.
April 13, 2023

Statin Primary Prevention Trial in HIV Halted for Efficacy

By Megan Brooks An international clinical trial testing statin therapy for primary cardiovascular prevention in people living with HIV has been stopped early due to strong […]
April 13, 2023

REPRIEVE Stopped: Big MACE Reductions With Statins in HIV+ Subjects

By Shelley Wood HIV is merely a “risk modifier” in current guidelines; these results pave the way for a new primary-prevention indication for statins. Read the […]
April 5, 2023

Identification of pre-infection markers and differential plasma protein expression following SARS-CoV-2 infection in people living with HIV

Abstract Background Mechanisms contributing to COVID-19 severity in people with HIV (PWH) are poorly understood. We evaluated temporal changes in plasma proteins following SARS-CoV-2 infection and […]
March 16, 2023

INSTI Use Beyond Two Years Not Associated With Greater Weight Gain in Global REPRIEVE Study

By Barbara Jungwirth People living with HIV (PLWH) taking integrase strand transfer inhibitors (INSTIs) gained more weight during the first two years of that regimen than […]
March 13, 2023

New insights into how patient factors and COVID-19 infection affect antibody responses in people with HIV

Press Release from Massachusetts General Hospital Read the full feature here.