Marissa Diggs

April 13, 2023

REPRIEVE Stopped: Big MACE Reductions With Statins in HIV+ Subjects

By Shelley Wood HIV is merely a “risk modifier” in current guidelines; these results pave the way for a new primary-prevention indication for statins. Read the […]
April 5, 2023

Identification of pre-infection markers and differential plasma protein expression following SARS-CoV-2 infection in people living with HIV

Abstract Background Mechanisms contributing to COVID-19 severity in people with HIV (PWH) are poorly understood. We evaluated temporal changes in plasma proteins following SARS-CoV-2 infection and […]
March 16, 2023

INSTI Use Beyond Two Years Not Associated With Greater Weight Gain in Global REPRIEVE Study

By Barbara Jungwirth People living with HIV (PLWH) taking integrase strand transfer inhibitors (INSTIs) gained more weight during the first two years of that regimen than […]
March 13, 2023

New insights into how patient factors and COVID-19 infection affect antibody responses in people with HIV

Press Release from Massachusetts General Hospital Read the full feature here.
March 1, 2023

Coronary Artery Plaque Composition and Severity Relate to the Inflammasome in People with Treated HIV

Abstract Inflammasome activation is increased in people with HIV (PWH), but its relationship with coronary plaque is poorly understood in this setting. In a large HIV […]
February 27, 2023

Changes in Body Mass Index with Longer-term Integrase Inhibitor Use: a Longitudinal Analysis of REPRIEVE data

Abstract Weight gain with longer-term INSTI-based regimens remains unknown. Over 2-years of follow-up in REPRIEVE, INSTI use was associated with weight gain among those on an […]
February 27, 2023

Impact of host factors and COVID-19 infection on the humoral immune repertoire in treated HIV

Abstract People with HIV (PWH) appear at higher risk for suboptimal pathogen responses and worse COVID-19 outcomes, but the effects of host factors and COVID-19 on […]
November 30, 2022

The importance of methods for site performance evaluation in REPRIEVE, a longitudinal, global, multicenter trial

Abstract Background REPRIEVE, the Randomized Trial to Prevent Vascular Events in HIV, is a multicenter, primary prevention trial evaluating whether a statin can prevent major cardiovascular […]
November 30, 2022

Ideal cardiovascular health, biomarkers, and coronary artery disease in persons with HIV

Abstract Objective To investigate relationships between Life’s Simple 7 (LS7), an assessment of cardiovascular health (CVH), and coronary plaque among people with HIV (PWH). Methods Coronary […]