In the News

June 1, 2019

REPRIEVE Rationale and Design Manuscript will be published in the American Heart Journal

Cardiovascular disease (CVD) is more frequent among people with HIV (PWH) and may relate to traditional and nontraditional factors, including inflammation and immune activation. A critical need exists to […]
October 5, 2018

Prism Health Teams with Harvard for Study

People living with HIV are developing heart disease at twice the rate of the general population, and Prism Health and Harvard Medical School want to know […]
September 10, 2018

Clinical trial seeks to prevent heart disease in those living with HIV

An international clinical trial, which is looking for effective ways to prevent heart disease in those living with HIV, has hit 7,000 participants. “It’s a major […]
May 7, 2018

Why Does HIV Pose a Greater Threat to Women’s Hearts?

HIV-related heart disease is a leading cause of death among people living with HIV — even when they are on consistent, effective HIV treatment. Researchers are […]
February 14, 2018

Happy Heart Month: What People Living with HIV Should Know

Today marks not just a time to exchange valentines and chocolates, but also the midpoint of American Heart Month(link is external). Did you know people living with […]
December 22, 2017

Exploring Barriers for Women in HIV Clinical Research With REPRIEVE

Throughout history, women have been excluded from clinical research studies, resulting in a dearth of knowledge about the effect that drugs might have on different sexes. […]
December 1, 2017

Cardiovascular disease: the next great challenge for HIV care

In the first World AIDS Day in 1988, the outlook was bleak for people living with this strange, new, and deadly disease. Few could imagine the […]
September 18, 2017

NIAID Supports Research Towards Healthy Aging for People Living with HIV

Today marks the 10th National HIV/AIDS and Aging Awareness Day. This annual observance brings attention to the unique social and health-related challenges of older people living […]
September 18, 2017

Preventing HIV-Related Heart Disease

As people living with HIV grow older, heart disease is emerging as a major public health problem despite effective treatments that suppress the virus and extend […]
June 17, 2017

HIV-1–Associated Atherosclerosis

Cardiovascular disease, including atherosclerosis and atherosclerosis-associated complications, is an increasing cause of morbidity and mortality in human immunodeficiency virus (HIV) patients in the post-antiretroviral therapy era. […]
May 28, 2017

Study explores way to stave off heart attacks in HIV patients

People infected with HIV can now live long, healthy lives — so long as they don’t have a heart attack. Cardiovascular problems among HIV patients are emerging as […]
April 24, 2017

New Findings Highlight the Potential Utility of Pitavastatin for People Living with HIV in Support of the REPRIEVE Trial

Stemming from the INTREPID Trial, three recently published papers give credence to pitavastatin’s ability to lower cholesterol and dampen inflammation in people living with HIV.
April 20, 2017

REPRIEVE is featured on Expresso morning show in South Africa

For years Medical researchers, government agencies and health institutes have been looking at ways to improve health outcomes of individuals living with HIV/AIDS. With the advent […]
March 8, 2017

Women are leading the way in HIV research

There is a saying in South Africa: Wathint’ abafazi, wathint’ imbokodo. You strike the women, you strike the rock. On International Women’s Day, we want to […]
February 28, 2017

US trial seeks HIV-positive South Africans for study

A US-funded study is recruiting South Africans to help find a way to prevent heart disease among HIV-positive people. Someone with HIV can have more than […]
February 22, 2017

Spotlight On: #HEARTHEALTH and People Living With HIV

February is heart health month, a perfect time to focus our attention on an important area of concern in the HIV community: cardiovascular health. People living […]
February 14, 2017

This February, Take Heart: NIH is Committed to Preventing HIV-Related Heart Attacks and Strokes

Antiretroviral therapy (ART) has transformed HIV infection from an almost-always fatal disease to what is now a manageable, chronic health condition. Today, a person diagnosed with […]
February 13, 2017

How to Make Preventing Heart Disease in HIV Fun and Exciting: The REPRIEVE Trial

The people researching cardiovascular disease in HIV have quite the challenge.Because when you think about it for a second, we HIV treaters are a pretty spoiled bunch […]
February 13, 2017

Campaign Launched to Get More Women Into HIV Heart Health Study

People with HIV seldom die of AIDS-related opportunistic infections anymore. Thanks to modern medicine called highly active antiretroviral therapy, or HAART, many people diagnosed with HIV […]
February 9, 2017

Can Statins Cut Heart Disease Risk in HIV Patients?

February is American Heart Month, and traditionally a time when organizations such as the American Heart Association ramp up initiatives to promote awareness of heart disease. […]
February 2, 2017

Should People With HIV Take a Statin?

HIV is linked to a higher heart disease risk. Research suggests statins can help. But definitive proof likely won’t come for another three years. Even when […]
December 1, 2016

The REPRIEVE Trial: The Last Word on Cardiovascular Disease in HIV-positive Persons (Hopefully)

Your 50 Year-old, female, HIV-positive patient, presents for a follow-up visit. She has heard that the risk of cardiovascular disease is increased among people living with […]
December 1, 2016

NIH Statement on World AIDS Day

This year, the world marked the 35th anniversary of the first published reports of what would come to be known as HIV/AIDS. This disease has wrought […]
November 23, 2016

Stopping a silent killer

“I had no idea that since I have HIV, I may be twice as likely to have a heart event compared to the general population,” said Frank […]
September 29, 2016

Woman-Centric Research and Why it’s Time to Listen to the Ladies

Earlier this month, AVAC hosted a webinar to explain and explore the complex issues of hormonal contraceptives and HIV risk in light of a new analysis that is generating […]
September 13, 2016

A Reprieve For Women: Embracing Inclusive Scientific Research

Historically, understanding a woman’s unique biology and developing optimal interventions for women has been somewhat of a blind spot for medical research. For much of the […]
June 17, 2016

REPRIEVE Trial Investigators Launch “Follow YOUR Heart” Campaign for Women Living with HIV

Research shows that women are often underrepresented in HIV clinical trials. In fact, astudy recently published in the Journal of Acquired Immune Deficiency Syndromes found that less […]
June 15, 2016

HIV and Heart Disease – NIH Explores the Connection

HIV-positive men and women can now live longer than ever before. A 2013 study found that a newly diagnosed 20-year-old on effective antiretroviral therapy (ART) can […]
April 29, 2016

Researchers evaluating HIV’s hidden heart threats

Human immunodeficiency virus infection is no longer the death sentence it was 30 years ago, but HIV-infected adults may face a new health hurdle – heart […]
April 14, 2016

REPRIEVE Heart Disease Trial Enrolls 1,200 Seeks Female Participants

The REPRIEVE trial, which will test a sort of “PrEP for heart disease” among 6,500 people with HIV at sites around the world, has already enrolled […]
March 30, 2016

Clinical trial addresses HIV and cardiovascular risks

Researchers at two area universities are among those participating in a nationwide clinical trial focused on HIV-related cardiovascular disease. University of Illinois at Chicago and Northwestern […]
March 4, 2016

Study looks at HIV/AIDS heart risk

Several Boston-area doctors will serve as primary investigators in a worldwide study on heart disease among HIV/AIDS patients — just one deadly upshot of an illness […]
January 6, 2016

New med Could Prevent Heart Disease in People with HIV

Call it a PrEP to protect against heart disease in people with HIV.A large, multi-site clinical trial dubbed REPRIEVE has begun enrolling across the U.S. and […]
December 14, 2015

Landmark Trial to Examine Cardiovascular Treatment in HIV Patients

Over the course of their careers, many clinicians have seen HIV/AIDS progress from extremely high short-term mortality to chronic, long-term disease management. As HIV patients are […]
December 1, 2015

World AIDS Day

Leadership from REPRIEVE: Randomized Trial to Prevent Vascular Events in HIV, would like to recognize World AIDS Day as a time to remember those we have lost to HIV/AIDS and also recognize the progress that has been made to help people with HIV live longer, healthier lives.
November 2, 2015

Sponsored by National Institutes of Health, the largest clinical trial ever focused on HIV-related cardiovascular disease is still seeking poz participants

As HIV-positive people continue living longer due to highly active antiretroviral therapy, cardiovascular disease has become a growing concern.  According to the National Institute of Allergy and […]
October 1, 2015

HIV-Related Cardiovascular Disease, Statins, and the REPRIEVE Trial

HIV infection is associated with increased cardiovascular disease (CVD), and increased rates of myocardial infarction and stroke have been observed in HIV-infected individuals. After traditional risk […]
October 1, 2015

Getting to the Heart of the Matter

HIV raises the risk of heart disease. What can you do to lower that risk?People with HIV are at a greater risk for heart disease than […]
August 18, 2015

Exploring Statins to Decrease HIV-Related Heart Disease Risk

Antiretroviral therapy (ART) has been a lifeline for untold numbers of patients with HIV. But as mounting evidence shows the infection may increase their risk of […]
July 30, 2015

REPRIEVE featured in JAMA

JAMA article highlights REPRIEVE trial for studying ways to prevent HIV-Related Heart Disease! Individuals living with HIV are at increased risk of heart disease.
July 27, 2015

REPRIEVE for Heart Disease in HIV

REPRIEVE was recently featured online in POZ. Click here to read more!
May 27, 2015

REPRIEVE and Washington University Featured in the St. Louis Post-Dispatch

Washington University's participation in the REPRIEVE trial is featured in the St. Louis Post-Dispatch!
May 1, 2015

Novel mechanisms and potential treatment strategies for CVD in HIV patients

Epidemiological studies suggest cardiovascular disease, including myocardial infarction and stroke, are increased 50% to 100% among HIV patients compared with non-HIV patients. Moreover, data suggest cardiovascular […]
April 24, 2015

Exciting News from MGH About the REPRIEVE Trial

Exciting news from Massachusetts General Hospital about the REPRIEVE trial!
April 15, 2015

NIH Announces REPRIEVE Trial Launch

NHLBI and NIAID announce launch of the REPRIEVE Trial:
March 13, 2015

Dr. Monica Shah Publishes on High Priority Research Including REPRIEVE Trial

Please see attached link to article “Stimulating High Impact HIV-Related Cardiovascular Research: Recommendations From a Multidisciplinary NHLBI Working Group on HIV-Related Heart, Lung, and Blood Disease” by Dr. Monica Shah published in the February 24, 2015 issue of the Journal of the American College of Cardiology.
March 11, 2015

Importance of REPRIEVE Trial Highlighted at CROI 2015

REPRIEVE Trial highlighted by Dr. Steven Grinspoon, Co-PI of the REPRIEVE Trial at HIV Conference/CROI 2015, in Seattle, WA.
March 10, 2015

Dr. Steven Grinspoon is Interviewed about REPRIEVE

At the 2015 Conference on Retroviruses and Opportunistic Infections (CROI Conference) in Seattle, Washington, Dr. Steven Grinspoon, Co-PI of the REPRIEVE trial, is interviewed on the topic of his plenary presentation: “Cardiovascular Disease in HIV Patients: An Emerging Paradigm and Call to Action”.
October 27, 2014

MGH: Can statin treatment cut cardiovascular risk in HIV-infected patients?

BOSTON – A nationwide study based at Massachusetts General Hospital (MGH) will investigate, for the first time, whether treatment with a statin drug can reduce the elevated risk of cardiovascular disease in individuals infected with the human immunodeficiency virus (HIV).
October 22, 2014

NY Times: “Heart Trouble Early and Often in H.I.V. Patients”

He was 29 when he began antiretroviral therapy.He was 43 when he had a heart attack.“I felt fluttery,” he said. “Weird and fluttery. It went away. I ignored it. A week later, it came back, and this time I felt something in my arm too. I was too stupid to call an ambulance. I got in a cab and went to the hospital.”